Variants of uncertain significance (VUS) remain a hot topic in genetic testing. But what exactly does it mean when a variant is classified as “of uncertain significance” and what does this result mean for my patient? In our annual VUS webinar, we will review how variants are classified and provide further guidance on what providers can do to advance reclassification.
This webinar is presented by Blueprint Genetics Laboratory Director Jennifer Schleit, PhD, FACMG. Case examples, recent publications, and current guidelines around VUS will be discussed as well.
- Review how variants are classified
- Examine what variants of uncertain significance mean for patients and providers
- Share insights on what providers and genetic counselors can do to advance reclassification of variants
- Review case examples
Jennifer Schleit, PhD, FACMG, received a PhD in pathology from the University of Washington in Seattle. She completed a clinical fellowship at the University of Washington and received her certification in clinical molecular genetics from the American Board of Medical Genetics and Genomics (ABMGG). Dr Schleit served as an Assistant Director at the Center for Precision Diagnostics at the University of Washington before accepting a position as senior geneticist at Blueprint Genetics in 2017. Her last position at Blueprint Genetics was as Laboratory Director of the Seattle facility until September 2022.
More details here