Customization of Diagnostic Panels

FLEX panels

Healthcare professionals can customize most of our panels by adding clinically relevant genes or by removing genes from the selected panel. Customized panels are called FLEX Panels. 

The panels can be customized by: 

  • Adding up to 200 genes from a list of >4000 clinically relevant genes from any medical specialty in the same phenotypic category as the test being ordered
  • Removing as many genes as desired (until a minimum of 2 remain) 

The customization of panels is intended to aid in establishing the molecular cause of the patient’s clinical presentation/phenotype. For example, your patient has a diagnosis of spastic ataxia. You can add genes from the hereditary spastic paraplegia panel to the ataxia panel to cover all the relevant genes.  

Adding genes unrelated to the patient’s phenotype for the purposes of carrier testing due to family history, predictive testing, or general population screening is not the intended use of panel customization. For example, an ataxia panel is being ordered due to a diagnosis of ataxia in the patient being tested. This patient also has a family history of breast cancer but does not have a personal history of cancer. Adding BRCA1 and BRCA2 to the ataxia panel is not the intended use of the customization feature.  

Customized panels can only be ordered through our online portal, Nucleus. Customized panels can be saved and named by each user. All saved panels will be stored in the “My Saved FLEX panels” list for later use. The saved panel will only be visible to the user who created it. 


There is no additional cost for panel flex customization.


Contact us with any questions. Our client services team, comprised of client service representatives, genetic counseling assistants, and genetic counselors, are happy to assist you with your custom panel questions.

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